Dec 31, 2018 · Clodronate should be swallowed whole with a full glass of plain tap water. Never take it with milk because this reduces the amount of clodronate your body can absorb. You need to drink plenty of fluids, such as water, while you are taking clodronate treatment. Always take clodronate tablets exactly as .
Jun 12, 2007 · Clinical trials have reported conflicting results on whether oral clodronate therapy improves survival in breast cancer patients. This study was undertaken to evaluate further the effect of oral clodronate therapy on overall survival, bone metastasis-free survival and nonskeletal metastasis-free Cited by: 123.
Clodronate does not interfere with bone mineralization. 4. On a molar basis, clodronate is 10 times less potent than pamidronate. 2. In malignancy -related hypercalcemia, clodronate decreases serum calcium by inhibiting tumour-induced bone resorption and reducing calcium flow from the resorbing bone into the blood. Clodronate also reduces.
Sodium clodronate is a tablet that’s given to reduce the risk of breast cancer spreading to the bones and other parts of the body. It belongs to a group of drugs called bisphosphonates. These drugs slow down or prevent bone damage. Sodium clodronate is also used to treat breast .